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Endocrinology & Metabolism news
Overweight & Obesity
Time-restricted eating vs. daily calorie restriction in reducing nonalcoholic fatty liver disease
Adults with obesity and nonalcoholic fatty liver disease did not see additional reductions in intrahepatic triglyceride while on a time-restricted eating regimen compared to subjects on a daily calorie-restriction diet. This ...
2 hours ago
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Diabetes
Researchers discover two subtypes of insulin-producing cells
A team led by Van Andel Institute and Max Planck Institute of Immunobiology and Epigenetics scientists has identified two distinct subtypes of insulin-producing beta cells, or ß cells, each with crucial characteristics that ...
3 hours ago
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Beneficial bacteria in the infant gut uses nitrogen from breast milk to support baby's health
A University of Massachusetts Amherst nutrition scientist who has spent his career studying breast milk has demonstrated how beneficial microbes in the gut of infants use nitrogen from human milk to support pediatric nutrition ...
11 hours ago
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Components of cytoskeleton found to strengthen effect of sex hormones
Researchers from Freiburg and Kiel discovered that actin acts in the cell nucleus and is partly responsible for the expression of male sexual characteristics
Mar 27, 2023
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Ovary removal when young could raise Parkinson's risk
Women who have both of their ovaries removed before age 43 have an increased risk of developing Parkinson's disease or parkinsonism, according to a recent study.
Mar 27, 2023
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Bendy joints, stretchy skin, clumsiness—why hypermobile Ehlers-Danlos Syndrome is often missed
There is growing interest in a connective tissue condition called Ehlers-Danlos Syndrome.
Mar 27, 2023
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Gender-affirming care has a long history in the US—and not just for transgender people
In 1976, a woman from Roanoke, Virginia, named Rhoda received a prescription for two drugs: estrogen and progestin. Twelve months later, a local reporter noted Rhoda's surprisingly soft skin and visible breasts. He wrote ...
Mar 27, 2023
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Sex-specific mechanisms for major depressive disorder identified in response to dysregulated stress hormones
Northwestern Medicine investigators have discovered novel sex-specific mechanisms that control how stress hormones impact dopamine transmission and motivation, findings that can inform new therapeutic strategies for treating ...
Mar 24, 2023
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Dieting: Brain amplifies signal of hunger synapses, finds study
Many people who have dieted are familiar with the yo-yo effect: after the diet, the kilos are quickly put back on. Researchers from the Max Planck Institute for Metabolism Research and Harvard Medical School have now shown ...
Mar 24, 2023
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Tools for more accurate obesity risk assessment based on sex, ethnicity
For decades, health care practitioners have used body mass index (BMI) as an indicator of a person's health. But this equation only considers height and weight, and may not capture an accurate picture of a person's risk for ...
Mar 23, 2023
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Researchers pave the way for solutions to problems affecting preterm infants
The time of birth brings many challenges to the newborn. Switching from a fetal life support system inside the uterus to postnatal life outside the uterus entails major changes in the function of multiple organs. For instance, ...
Mar 23, 2023
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Sweets change our brain: Why we can't keep our hands off chocolate
Chocolate bars, crisps and fries—why can't we just ignore them in the supermarket? Researchers at the Max Planck Institute for Metabolism Research in Cologne, in collaboration with Yale University, have now shown that foods ...
Mar 22, 2023
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Scientists uncover protective role of NAD maintenance in kidney disease
Roughly one million people die of untreated kidney failure, worldwide, each year. Despite the major personal and economic burden, only a few new approaches have been deployed to treat or cure kidney disease over the last ...
Mar 22, 2023
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Brown fat may help improve cancer survival rates
Brown fat is not linked to cancer-associated loss of body weight and muscle mass, a common condition known as cachexia, according to a new joint study from The Rockefeller University and Memorial Sloan Kettering Cancer Center ...
Mar 22, 2023
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Obesity risk may pass from mothers to daughters
Women with obesity may share risk for the disease with their daughters, but not their sons, according to a new study published in the Journal of Clinical Endocrinology & Metabolism.
Mar 21, 2023
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Alzheimer's disease: Problems with the brain's energy supply could be a cause
Scientists have been working to understand the root causes of dementia and Alzheimer's disease for decades now. But one of the reasons we don't yet have a cure for this disease is because of the complexity of the human brain—alongside ...
Mar 21, 2023
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Researchers find a source of depression linked to a single enzyme
Researchers at Wuhan University in China have found a previously unknown mechanism linking gut bacteria, estradiol, and depression in women. The study, "Gut-microbiome-expressed 3b-hydroxysteroid dehydrogenase degrades estradiol ...
Biological BMI: Researchers dig deep into data to determine better measures of metabolic health
Institute for Systems Biology (ISB) researchers have constructed biological body mass index (BMI) measures that offer a more accurate representation of metabolic health and are more varied, informative and actionable than ...
Mar 20, 2023
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Excess calories during development may alter the brain and spur adult overeating
People whose mothers are overweight during pregnancy and nursing may become obese as adults because early overnutrition rewires developing brains to crave unhealthy food, according to a Rutgers study in Molecular Metabolism.
Mar 20, 2023
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Understanding how exercise induces systemic metabolic benefits
Northwestern Medicine scientists have uncovered a mechanism by which exercise activates metabolic benefits in the body, according to a new study published in Cell Metabolism.
Mar 16, 2023
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