Systems Biology Collection

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CommentaryMarch 8, 2023
Chemical disaggregation of alpha-synuclein fibrils as a therapy for synucleinopathies
This is an addendum toComplex viscosity of helical and doubly helical polymeric liquids from general rigid bead-rod theory
Research ArticleMarch 1, 2023
State- and stimulus-specific dynamics of SMAD signaling determine fate decisions in individual cells
- Stefan Bohn,
- Lorenz Hexemer,
- Zixin Huang,
- Laura Strohmaier,
- Sonja Lenhardt,
- Stefan Legewie,
- Alexander Loewer,
This is an addendum toComplex viscosity of helical and doubly helical polymeric liquids from general rigid bead-rod theory
Research ArticleFebruary 9, 2023
Small molecules disaggregate alpha-synuclein and prevent seeding from patient brain-derived fibrils
- Kevin A. Murray,
- Carolyn J. Hu,
- Hope Pan,
- Jiahui Lu,
- Romany Abskharon,
- Jeannette T. Bowler,
- Gregory M. Rosenberg,
- Christopher K. Williams,
- Gazmend Elezi,
- Melinda Balbirnie,
- Kym F. Faull,
- Harry V. Vinters,
- Paul M. Seidler,
- David S. Eisenberg,
This is an addendum toComplex viscosity of helical and doubly helical polymeric liquids from general rigid bead-rod theory
LetterJanuary 9, 2023
Rebound increase in circulating dipeptidyl peptidase 4 (DPP4) enzyme activity after acute COVID-19
- Gábor Firneisz and
This is an addendum toComplex viscosity of helical and doubly helical polymeric liquids from general rigid bead-rod theory
ReplyJanuary 9, 2023
Reply to Firneisz: “Rebound increase in circulating dipeptidyl peptidase-4 (DPP4) enzyme activity after acute Covid-19”
- Shu-Hai Lin,
- Zhu Yang,
This is an addendum toComplex viscosity of helical and doubly helical polymeric liquids from general rigid bead-rod theory
Research ArticleJanuary 6, 2023
Perfect adaptation achieved by transport limitations governs the inorganic phosphate response in S. cerevisiae
- Hon Ming Yip,
- Shiyu Cheng,
- Evan J. Olson,
- Michael Crone,
- Sebastian J. Maerkl and
This is an addendum toComplex viscosity of helical and doubly helical polymeric liquids from general rigid bead-rod theory
Research ArticleDecember 28, 2022
Robotic data acquisition with deep learning enables cell image–based prediction of transcriptomic phenotypes
- Jianshi Jin,
- Taisaku Ogawa,
- Nozomi Hojo,
- Kirill Kryukov,
- Kenji Shimizu,
- Tomokatsu Ikawa,
- Tadashi Imanishi,
- Taku Okazaki,
- Katsuyuki Shiroguchi,
This is an addendum toComplex viscosity of helical and doubly helical polymeric liquids from general rigid bead-rod theory
Research ArticleDecember 19, 2022
Glacial meltwater determines the balance between autotrophic and heterotrophic processes in a Greenland fjord
- Mikael K. Sejr,
- Annette Bruhn,
- Tage Dalsgaard,
- Thomas Juul-Pedersen,
- Colin A. Stedmon,
- Martin Blicher,
- Lorenz Meire,
- Kenneth D. Mankoff,
- Jakob Thyrring,
This is an addendum toComplex viscosity of helical and doubly helical polymeric liquids from general rigid bead-rod theory
Research ArticleDecember 1, 2022
Comprehensive mapping of alternative polyadenylation site usage and its dynamics at single-cell resolution
- Junliang Wang,
- Wei Chen,
- Wenjun Yue,
- Wenhong Hou,
- Feng Rao,
- Hanbing Zhong,
- Yuanming Qi,
- Ni Hong,
- Ting Ni,
- Wenfei Jin,
This is an addendum toComplex viscosity of helical and doubly helical polymeric liquids from general rigid bead-rod theory
Research ArticleOctober 24, 2022
Input integration by the circadian clock exhibits nonadditivity and fold-change detection
- Gal Manella,
- Nityanand Bolshette,
- Marina Golik,
- Gad Asher and
This is an addendum toComplex viscosity of helical and doubly helical polymeric liquids from general rigid bead-rod theory

Science Sessions Podcast February 18, 2013

Microbial cell factories

Bernhard Palsson explains how bacteria can be used as factories to produce sustainable products.

Thomas D. Albright
Salk Institute for Biological Studies
Emery N. Brown
Massachusetts Institute of Technology
Edward Callaway
Salk Institute for Biological Studies
Charles D. Gilbert
The Rockefeller University
Michael E. Goldberg
Columbia University
Tony Movshon
New York University
Marcus E. Raichle
Washington University in St. Louis
Terrence J. Sejnowski
Salk Institute for Biological Studies
Peter L. Strick
University of Pittsburgh

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Systems Biology

Recent articles

Chemical disaggregation of alpha-synuclein fibrils as a therapy for synucleinopathies

State- and stimulus-specific dynamics of SMAD signaling determine fate decisions in individual cells

Small molecules disaggregate alpha-synuclein and prevent seeding from patient brain-derived fibrils

Rebound increase in circulating dipeptidyl peptidase 4 (DPP4) enzyme activity after acute COVID-19

Reply to Firneisz: “Rebound increase in circulating dipeptidyl peptidase-4 (DPP4) enzyme activity after acute Covid-19”

Perfect adaptation achieved by transport limitations governs the inorganic phosphate response in S. cerevisiae

Robotic data acquisition with deep learning enables cell image–based prediction of transcriptomic phenotypes

Glacial meltwater determines the balance between autotrophic and heterotrophic processes in a Greenland fjord

Comprehensive mapping of alternative polyadenylation site usage and its dynamics at single-cell resolution

Input integration by the circadian clock exhibits nonadditivity and fold-change detection

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Microbial cell factories

Editors

Thomas D. Albright

Emery N. Brown

Edward Callaway

Charles D. Gilbert

Michael E. Goldberg

Tony Movshon

Marcus E. Raichle

Terrence J. Sejnowski

Peter L. Strick

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Further Reading

Adaptive response by state-dependent inactivation

Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism

Structure of deviations from optimality in biological systems

The biomass distribution on Earth

The total number and mass of SARS-CoV-2 virions

A scalable pipeline for designing reconfigurable organisms

The biomass distribution on Earth

Histone H3K27ac separates active from poised enhancers and predicts developmental state

rMATS: Robust and flexible detection of differential alternative splicing from replicate RNA-Seq data

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